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Zhongdong Huang Selected Research

PEGPH20

11/2019The growth of a xenograft breast cancer tumor model with engineered hyaluronan-accumulating stroma is dependent on hyaluronan and independent of CD44.
2/2015Tumor-associated hyaluronan limits efficacy of monoclonal antibody therapy.
1/2014Accumulation of extracellular hyaluronan by hyaluronan synthase 3 promotes tumor growth and modulates the pancreatic cancer microenvironment.
4/2012Effective targeting of the tumor microenvironment for cancer therapy.

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Zhongdong Huang Research Topics

Disease

8Neoplasms (Cancer)
11/2019 - 01/2009
3Breast Neoplasms (Breast Cancer)
11/2019 - 08/2014
2Non-Small-Cell Lung Carcinoma (Carcinoma, Non-Small Cell Lung)
01/2014 - 04/2012
1Squamous Cell Carcinoma of Head and Neck
02/2015
1Chromosomal Instability (Chromosome Stability)
08/2014
1Triple Negative Breast Neoplasms
08/2014
1Inflammation (Inflammations)
06/2014
1Pancreatic Neoplasms (Pancreatic Cancer)
01/2014
1Hypoxia (Hypoxemia)
01/2014

Drug/Important Bio-Agent (IBA)

4Hyaluronoglucosaminidase (Hyaluronidase)FDA Link
11/2019 - 01/2014
4PEGPH20IBA
11/2019 - 04/2012
4Hyaluronic Acid (Hyaluronan)IBA
11/2019 - 04/2012
2Small Interfering RNA (siRNA)IBA
11/2019 - 08/2014
2Hyaluronan SynthasesIBA
11/2019 - 01/2014
2GlycosaminoglycansIBA
01/2014 - 04/2012
1Tyrosine Kinase InhibitorsIBA
10/2018
1SolventsIBA
10/2018
1repotrectinibIBA
10/2018
1Pharmaceutical PreparationsIBA
10/2016
1Cetuximab (Erbitux)FDA Link
02/2015
1Trastuzumab (Herceptin)FDA Link
02/2015
1Monoclonal AntibodiesIBA
02/2015
1PF-2771IBA
08/2014
1centromere protein EIBA
08/2014
1taxaneIBA
08/2014
1Histones (Histone)IBA
08/2014
1KinesinsIBA
08/2014
1LipopolysaccharidesIBA
06/2014
1EndotoxinsIBA
06/2014
1Cadherins (E-Cadherin)IBA
01/2014
1CateninsIBA
01/2014
1Proteins (Proteins, Gene)FDA Link
01/2014
1Sequestering AgentsIBA
01/2009
1ErbB Receptors (EGF Receptor)IBA
01/2009
1LigandsIBA
01/2009

Therapy/Procedure

4Therapeutics
02/2015 - 01/2009
1Immunotherapy
02/2015